Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma
Novel sensitive methods for early detection of relapse and for monitoring therapeutic efficacy may have
a huge impact on risk stratification, treatment, and ultimately outcome for patients with bladder cancer. We
addressed the prognostic and predictive impact of ultra-deep sequencing of cell-free DNA in patients before and
after cystectomy and during chemotherapy.
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